The correct interpretation of sperm DNA fragmentation test

The correct interpretation of sperm DNA fragmentation test

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We read the commentary by Dr. Ferlin with interest (1). The author first stated the drawbacks of semen analysis in the diagnosis of male infertility and the need for sperm function tests. It is followed by illustrating the limitation of the current evidence in supporting the routine use of sperm DNA fragmentation (SDF...

The debate on sperm DNA fragmentation test goes on

The effect of rhFSH on Sperm DNA Fragmentation and sperm parameters in Oligozoospermia Infertile Men

Background: One of the main causes of male infertility is the negative effects of oxidative stress. Follicle-stimulating hormone (FSH) plays an essential role in spermatogenesis, as well as in the maintenance of sperm DNA integrity. This study aimed to determine whether the recombinant human follicle-stimulating hormone (rhFSH) treatment of sperm parameters could positively affect sperm DNA and...

Application of sperm DNA fragmentation test in clinical setting

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. The concise guideline by the expert panel of andrologists/ urologists has described the various tests used to determine sperm DNA fragmentation (SDF), their drawbacks and benefits. In addition, they have used a problem-based approach to illustrate the clinical utility of SDF (1). In couples with subfertility, male fac...

Call for wider application of sperm DNA fragmentation test